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统计学意义与临床意义距离有多远?——医学文献中统计分析结果解读需仔细 被引量:6

Significant difference, statistically or clinically——Pay more attention to the statistical analysis in medical references
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摘要 临床医学科研离不开统计学。只有了解该研究资料的特点,所选择变量的性质,注意%和95%可信限的关联和统计学意义与临床意义的差别,强调机制评估的重要性,才能对统计分析结果的临床意义作恰如其分的解释。 We can not do any clinical research if knowing nothing of statistics. In order to understand the results from a clinical research, readers must know the characteristics of the data, the features of the selected variables, the relation between % and 95% confidence interval, as well as the definitions of difference in clinical and statistical analysis, and it may be more important to make the evaluation of mechanism based on suitable explanation of clinical significance by means of statistical results.
作者 李光伟
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2006年第1期1-3,共3页 Chinese Journal of Endocrinology and Metabolism
关键词 统计学 统计学差异 临床意义 Statistics Statistic difference Clinical significance
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参考文献5

  • 1Turner RC,Millns H,Neil HA,et al.Risk factors for coronary artery disease in non-insulin dependent diabetes mellitus:United Kingdom Prospective Diabetes Study (UKPDS:23).BMJ,1998,316:823-828.
  • 2Hoogwerf B J,Waness A,Cressman M,et al.Effects of aggressive cholesterol lowering and low-dose anticoagulation on clinical and angiographic outcomes in patients with diabetes:the Post Coronary Artery Bypass Graft Trial.Diabetes,1999,48:1289-1294.
  • 3Knowler WC,Barrett-Connor E,Fowler SE,et al.Diabetes prevention program research group.Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.N Engl J Med,2002,346:393-403.
  • 4Heart Protection Study Collaborative Group.MRC/BHF heart protection study of antioxidant vitamin supplementation in 20 536 high-risk individuals:a randomised placebo-controlled trial.Lancet,2002,360:2-3.
  • 5Grundy SM,Cleeman JI,Merz CN,et al.Coordination Committee of the National Cholesterol Education Program.Implications of recent clinical trials for the National Cholesterol Education Program Adult treatment Panel Ⅲ Guidelines.J Am Coll Cardiol,2004,44:720-732.

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