小剂量氯胺酮复合咪达唑仑麻醉对剖宫产新生儿血气分析的影响

The effect of small dose of ketamine intravenous anesthesia using in cesarean on the blood-gas analysis of newborn umbilical control blood.

目的小剂量氯胺酮静脉复合麻醉对剖宫产新生儿的影响。方法Ⅰ组(实验组):选择有硬膜外麻醉禁忌证剖宫产病人30例,采用小剂量氯胺酮复合咪达唑仑麻醉:咪达唑仑0.04mg/kg,氯胺酮0.5mg/kg静脉注射,胎儿娩出后,酌情追加氯胺酮、异丙酚维持麻醉。Ⅱ组(对照组)30例:Ⅰ组每例后第1例硬膜外麻醉剖宫产组成。观察两组麻醉效果、不良反应、BP、HR、SpO2、新生儿脐带血气分析及新生儿Apgar评分。结果两组麻醉方法均能满足手术要求,Ⅰ组病人均不能回忆手术经过,无呕吐发生,两组脐带血气分析及新生儿Apgar评分无显著性差异(P>0.05),硬膜外麻醉组血流动力学改变显著(P<0.05)。结论小剂量氯胺酮复合咪达唑仑静脉麻醉能满足剖宫产手术要求,对新生儿无明显影响。

Objective To investigate the effect of ketamine intravenous anesthesia using in cesarean on newborn baby.Methods 30 pregnant women with Epidural block contraindications were selected for the study group,the Small-Dose ketamine intravenous anesthesia was applied.Midazolam 0.04mg/kg,ketamine 0.5mg/kg,iv,add the ketamine or propofol to maintatin effect.Another 30 cases were selected for control gooup,fit to Epidural block.We campared the anesthesia effect.untoward effect,BP.HR.SpO_2.the blood-gas analysis of newborn umbilical.and the Apgar.Results Both of the two anesthesia can satisfacted the need of cesarean.the study group can't remember the course of events,no vomit.the blood-gas analysis of newborn umblilical.and the Apgar were no obvious difference(P>(0.05)),the contral group's indicts of hemodynamics were stable(P<0.05).Conclusion Using small dose of Epidural and Midazolam intravenous anesthesia can fit the need of the cesarean and didn't affect the newborn baby.