红花与酚妥拉明治疗肺心病急性加重期疗效分析

Analysis the Effect of safflower and Phentolamine on severe acute Pulmonary Heart Disease

目的：探讨红花注射液与酚妥拉明治疗肺心痛急性加重期的疗效和安全性。方法：符合肺心病诊断的40例患者，随机分为治疗组和对照组，对照组为常规治疗组，治疗组在常规治疗的基础上加用红花注射液10～15ml＋5％GS250ml静滴，1次／d，连用14d；酚妥拉明10mg＋5％GS250ml静滴，15—20滴／min，1次／d，连用5～7d，治疗前后行血气和血液流变学检测，2周后判定疗效。结果：治疗前两组血液流变学和血气分析均无差异，治疗后治疗组明显改善，两组疗效比较，有显著差异（P〈0．05）。结论：红花、酚妥拉明合用疗效好，副作用少。

Objective ： To study the effect and safety of safflower injection and phentolamine in treating severe acute pulmonary heart disease. Method ： 40 cases were divided into treating group and comparing group randomly. The comparing group were adopted the routine method. In the treating group , 10 - 15 ml safflower injection and 250ml 5% GS were taken intravenous infusion in addition to the routine method . Once a day for 14 days 250ml 5% GS and 10mg phetolamine were taken intravenous infusion with 15 - 20drip/min for 5 -7 days once a day. The sap and haemorheology were detected before and after the treatment . and then evaluate the effect 2 weeks later. Result： There＇ s no difference on haemorheology and sap before treatment in both groups. It was improved after treatment in treating group. There＇ s significant difference comparing the both groups （ p 〈 0.05 ） o Conclusion ： It＇ s effective and with little side effect for the combination of safflower and phentolamine.