人工栽培南方红豆杉紫杉烷成分的研究

Structure of Taxanes of Cultivated Taxus chinensis var.mairei

采用溶剂萃取及多种色谱技术分离纯化,从人工栽培南方红豆杉中分离得到紫杉醇(Ⅰ)、2′-乙酰氧基-7-表-紫杉醇(Ⅱ)、(3E,7E)-2,α10,β13α-三乙酰基-5,α20-二羟基-3,8-断紫杉烷-3,7,11-三烯-9-酮(Ⅲ)和7-表-紫杉醇(Ⅳ),其中化合物(Ⅱ)首次从南方红豆杉分离得到。

It is reported that the isolation of four compounds,taxol （ Ⅰ ）, 2＇-acetoxy-7-epi-taxol （ Ⅱ ）, （ 3E, 7E）-2α,10β,13α-triacetoxy-5α, 20-dihydroxy-3, 8-secotaxa-3, 7, 11-trien 9 one （ Ⅲ ）, and 7-epi- Taxol （Ⅳ） from Taxus chinensis var. mairei and their structures are determined by spectroscopic analyses,especially NMR. Compound Ⅱ was got from Taxus chinensis var. mairei for the first time.