16层螺旋CT检测冠状动脉钙化斑块的狭窄程度

Researching the Character and Stenosis of Coronary Calcified Plaques by Using 16-slice Spiral CT

目的探讨冠状动脉钙化斑块的影像学特点及其与狭窄程度的关系。方法回顾性分析了20例经16层螺旋CT冠状动脉成像发现钙化斑块并接受冠状动脉造影患者的影像学资料。结果16层螺旋CT冠状动脉成像共发现钙化斑块84个,其中单纯小点钙(直径<0.15cm)16个,局部几乎无狭窄;单纯钙化斑块(直径≥0.15cm)56个,平均直径(0.27±0.09)cm,钙化斑块直径与局部管腔直径之比(C/V值)为0.85±0.33,75%的斑块狭窄程度小于50%,其狭窄程度与斑块直径及C/V值均无显著相关性(P>0.05);含钙化成分的混合斑块12个,其狭窄程度与混合斑块关系较密切。结论大部分钙化斑块表现为轻度狭窄,其狭窄程度与斑块直径无关,含钙化成分的混合斑块狭窄程度与混合斑块特点关系较密切。

Objective To explore the characters of coronary calcified plaques by using 16-slice spiral CT and determine their stenosis degree according to the results of catheter coronary angiography. Methods Twenty patients who had received 16-slice spiral CT coronary angiography and conventional coronary angiography （CAG） were found to be with calcified plaques. The characters of these plaques, including the diameter of calcified plaques and lumen diameter of the exact artery segment, were retrospectively analyzed. The stenosis degree of the corresponding segment was judged in accordance with the results of CAG. Results Totally 84 calcified plaques were observed in 16-slice spiral CT images in these 20 patients. Among them there were 16 small nodules （diameter： 〈 0. 15 cm）, 56 purely calcified plaques （diameter： ≥ 0. 15 cm）, and 12 complex plaques with calcify component. There was no obvious stenosis in artery segments with little calcified nodules. The stenosis degree of most segments with purely calcified plaques （75%） was less than 50% . The stenosis degree had no significant correlation with the size of plaques （ P 〉 0.05 ）. However, the stenosis degree of complex plaques had much closer relationship with the characters of mixed plaques. Conclusions Most coronary segments with calcified plaques have slight stenosis. Their stenosis degree is not related with the size of plaques. The stenosis degree of complex plaques has a closer relationship with the characters of mixed plaques.