泌尿系肿瘤患者红细胞免疫粘附功能的实验研究

RBC immune adherence activities in patients with tumors of urinary system

检测４１例泌尿系肿瘤患者的红细胞免疫粘附功能，以探讨该肿瘤的生物学特性与此项功能的关系。结果表明，Ｃ３ｂ受体在肿瘤组明显降低（Ｐ＜０．００１），膜ＩＣ水平在肿瘤组升高（ｐ＜０．００１）。肿瘤切除后红细胞免疫粘附可恢复正常。血沉可反映出肿瘤的红细胞免疫粘附功能状态。肿瘤分期、分级可反映膜ＩＣ水平，而对Ｃ３ｂ受体水平无影响。认为泌尿系肿瘤患者的红细胞免疫粘附功能的测定对评价该肿瘤病人预后有一定意义。

RBC immune adherence activities were studied in 41 patients with tumors of the urinary system.C3b receptor was significantly decreased in tumor bearers(p<0.001)and membranous IC was increased(P<0.001). The RBC immune adherence activities would return to normal after surgical extirpation of the tumor.Erythrocyte sedimentation rate (ESR) may partly denote the RBC immune adherence condition. The membranous IC level has been higher in the invasive tumor group and in the badly differentiated tumor group(P<0. 001).It was concluded that the assessment of RBC immune adherence plays an important role in evaluating the prognosis of patients with tumor of urinary system.