前列腺特异抗原在前列腺癌诊治中的意义

Serum prostate specific antigen and prostatic carcinoma

应用酶联免疫检查法测定４７例前列腺癌患者血清ＰＳＡ值。探讨ＰＳＡ在前列腺癌诊断、鉴别诊断、疗效监测等方面的意义。结果表明：血清ＰＳＡ与ＡＣＰ、ＡＫＰ比较，ＰＳＡ对前列腺的诊断敏感性为８９．３６％，ＡＣＰ、ＡＫＰ的敏感性分别为２０．４５％、１３．６０％。血清ＰＳＡ对前列腺癌临床分期、肿瘤分级具有参考价值。随访观察３８例前列腺癌患者治疗４～６周后ＰＳＡ值，结果显示：ＰＳＡ可作为前列腺癌疗效监测有价值的指标。

Serum prostate specific antigen(PSA)assay has been carried out by immuno-enzymatic technique in 47 patients with prostatic carcinoma. The sensitivity of PSA assay in the detection of prostatic carcinoma was 89.36% while it was only 20.45% and l3.60% for ACP and AKP. The serum PSA level was also relevant to the clinical staging and pathological grading of the Tumor. 38 patients managed by endocrine therapy have been followed up for 4￣6weeks with assay of serum PSA. It was claimed that, erum PSA assay was valuable in the detection, differrential diagnosis and monitoring of prostatic carcinoma.