广州市1992～2004年人间布鲁氏菌病监测分析

Analysis of Human Brucellosis Surveillance in Guangzhou from 1992 to 2004

目的掌握广州市人间布鲁氏菌病流行规律及分布状况,为今后制定防治策略提供科学依据。方法1992～1994年采用试管凝集试验(SAT),每年监测一次,以后每2～3年覆盖一次。1997年开始采用虎红凝集试验作为筛选,阳性者血清送广东省疾病预防控制中心做进一步诊断。结果1992～2004年血清学共检测19619,阳性14人,阳性率为0.07%;感染病例主要分布于番禺区;男女均可感染;以兽医、饲养员等职业较多;感染年龄在20～50岁。结论经过多年努力,广州市布鲁氏菌病达到稳定控制标准,其综合防治策略取得显著效果,但仍要坚持长期的人畜布病监测。

Objective To analyze the epidemiological characteristics of human brucellosis in Guangzhou to provide scientific evidence for future preventive and control measures. Methods Surveillance was carried out by Slow Tube Agglutination Test （SAT） one time every year in 1992-1994 and every 2-3 years in later years. In 1997, screening had been begun by Rose Bengel Plat Test（RBPT）. The positive serum had been diagnosed by Lab of Center for Disease Control and Prevention of Guangdong province. Results Serological test results showed that in 1992 to 2004, 14 out of 19619 persons were positive for brucellosis, with a positive rate of 0.07%. The most cases were distributed in Panyu District. Both sex would be infected. The infected people are mainly veterinarian and stock man of the age from 20 to 50. Conclusions Through comprehensive preventive and control measures, human brucellosis has been effectively under control in Guangzhou. However, to consolidate the success that already has been achieved, surveillance of brucellosis among human being and animals should be continued on a long-term basis.