无症状性脑梗死和血管性痴呆

Asymptomatically Cerebral Infarction and Vascular Dementia

目的探讨无症状性脑梗死(ACI)与血管性痴呆(VD)的关系.方法对2000～2004年有短暂性脑缺血发作(TIA)史或有眩晕、头痛而无明确卒中病史的300例60岁以上的老年人做了CT或MRI检查,并对68例影像学检查有ACI者做了简易智能状态检查(MMSE)和老年认知功能测验.结果做CT检查的200例老年人显示有ACI者33例(占16.5%),做MRI检查的100例显示有ACI者35例(占35%),68例有ACI患者有63例做了心理学测验,得分均低于非ACI者.结论ACI并非无临床症状,只是症状轻微、短暂,ACI患者绝大多数都有不同程度的认知功能障碍,最终将演变成血管性痴呆.

Objective To explore the relationship between asymptomatically cerebral infarction （ACI） and vascular dementia （VD）. Methods From 2000 to 2004, 300 senile patients（≥60 years old） with transient ischemic attack （TIA） or vertigo and headache（without obvious stroke） received CT or MRI. Then MMSE and senile person＇s cognitive function measurement were used in 68 patients with ACI diagnosed by imagery examination. Results 200 senile patients received CT and 33 patients were diagnosed as （16.5%）. 100 senile patients received MRI and 35 patients were diagnosed as ACI （35%）. Among 68 patients with ACI, 63 were received the test of psychological measurement and their scores were lower than those of the patients without ACI. Conclusions The symptoms of ACI were slight and transient. Most patients with ACI have cognitive dysfunction with different levels and maybe evolve to vascular dementia.