地奥紫黄精片免疫调节作用研究

Study on the immunomodulatory action of Di′ao ZHJ Tablets (地奥紫黄精片)

目的研究地奥紫黄精片对免疫功能的影响。方法应用正常及环磷酰胺所致免疫低下小鼠模型,分别采用MTT、ELISA法测定地奥紫黄精片对淋巴细胞增殖和分泌INF-γ、IL-2的影响。结果地奥紫黄精片显著增强正常及免疫低下小鼠淋巴细胞转化和增殖能力,升高淋巴细胞上清液中INF-γ和IL-2水平,增加免疫低下小鼠的脾指数、胸腺指数。结论地奥紫黄精片具有显著增强机体免疫功能的作用。

Objective： To investigate the immunomodulatory effects of Di＇ao ZHJ tablets on normal and hypo-immunity mice. Methods： The lymphocyte proliferation was evaluated by MTY assay, the inducing secretion of INF-γ and IL-2 in mice lymphocyte was performed by ELISA. Results： Di＇ao ZHJ tablets could enhance the lymphocyte proliferation and promote secretion of INF-γ and IL-2 in the no,＇mal and hypo-immunity mice significantly and increase the index of spleen and thymus in mice of hypo-im/nunity induced by Cy. Conclusion： Di＇ao ZHJ tablets could improve the immunological function significantly.