摘要
本文采用放射免疫法对１８例胃癌患者，６８例肝硬化患者及８９例其它各类胃良性疾病患者进行了基础状态下血清胃泌素水平的测定。结果显示：胃癌患者的血清胃泌素水平（７３．６６±４２．８６ｎｇ／Ｌ）明显低于各良性胃疾病组（Ｐ＜０．０１），与本组患者多为胃窦部肿瘤有关。肝硬化组血清胃泌素浓度（８１．３±３６．６５ｎｇ／Ｌ）较浅表性胃炎组低（１１８．７５±５５．１８ｎｇ／Ｌ，Ｐ＜０．０１），提示肝硬化病人亦存在低胃泌素血症。
The fundamental serum level of gastrin was detected by Radioimmunoassay in 18 cases of gastric cancer,68 casesof liver cirrhosis and 89 cases of other benign alilnentary canal diseases.The results indicated that the fundamental serum levels ofgastrin in gastric cancer group(73.66±42.86ng/L) were significantly lower than those in benign alimentary canal disease group(P<0.01).The reason was that the turnors were mainly located in pyloric antrum,The serum levels of gastrin in patients withliver cirrhosis(81. 3±36.65ng/L)were also significantly lower than those in superficial gastritis group(ll8.75±55;18ng/L)(P<0.01),suggesting that the hypo-gastrinmia existed in liver cirrhosis.
