尿液混合细胞群的形态观察及其临床意义

Morphological observation of urinary mixed cell group and it′s clinical value

目的探讨尿液混合细胞群(MIXED CELL GROUP,MCG)在肾盂肾炎诊断中的意义。方法以形态学方法观察578例泌尿系疾病患者的尿液沉渣涂片的MCG,并以荧光的着色及细胞染色的方法对细胞的类别进行判定,同时对白细胞管型、白细胞数量及尿沉渣中活菌数量作了对照比较。结果只有肾盂肾炎尿中出现MCG,急性肾盂肾炎阳性率为88.2%,慢性肾盂肾炎阳性率为96.7%。膀胱炎、尿道炎、前列腺炎、各类肾炎等尿沉渣中未见到MCG。结论MCG是一群细胞聚集黏附成团的细胞群体,对泌尿系感染患者的尿液中MCG的观察,有助于泌尿系感染部位来源的鉴别及肾盂肾炎的诊断,在肾盂肾炎的鉴别诊断方面具有重要的临床意义。

Objective To investigate the correlation between the morphological features of urinary mixed cell group（MCG） and the clinical outcome of pyelonephritis. Methods The mixed cell groups（MCG） were examined in the urinary sediments of 488 patients with the urinary system diseases with the morphological method. The fluorescent staining and the cellular staining were used for determining the types of the cells. Meanwhile, the leucocyte cast, the number of leucocytes and the number of the living bacteria were treated as the control. Results The MCG occurred only in the urine of pyelonephritis. The positive incidence was 88. 2% in the acute pyelonephritis and 96. 7% in the chronic pyelonephritis. No MCG were found in the urines of cystitis, urethritis, proatatitis, and any types of nephritis. Conclusion The examination of urinary MCG plays an important role in the differential diagnosis of pyelonephritis.