气相色谱法测定PVC输液袋中DEHP的含量

Gas chromatographic determination of DEHP in PVC infusion bags

目的 建立PVC输液袋中DEHP含量测定方法。方法 采用气相色谱法。色谱柱：HP-1（5m×0．53mm×2．65μm）毛细管柱，检测器：FID，进样口温度．300℃，检测器温度：300℃，柱温：280℃，载气流速：氮气：10ml／min。结果 DEHP在2．5～20mg／ml范围内与峰面积有良好线性关系，r=0．9970，平均回收率为101．1％（n=5），RSD=2．3％。结论 本方法准确、快速、简便且重现性好，可作为PVC输液袋中DEHP含量测定方法。

Objective To develolp a method to determine di（2- ethylhexyl） phthahte （DEHP） in polyvinly ehloride （PVC） infusion hags.Methods Analysis was perfonnod in a gas chromatograph using flame ionization detector.The determination conditions were as follows： column,Hp- 1（5 m×0.53 mm×2.65 μm）; injection temperature,300℃; coloumn temperature,280℃ ; detector temperature, 300℃; gas flow rate, N2 10 mL/min.Reasults The linear range of calibration curve of DEHP concentration and peak area was 2.5 ～ 20 mg/ml（ r = 0.9970）.The average recovery of DEHP was 101.1% （ n = 5） and RSD was 2.3%. Conclusion The method is aecurate,rapid and simple. The precision is high. It can be used for continUing DEHP in the PVC infusion hags.