摘要
瞄准：在经历 gastros 拷贝和结肠镜检查的病人上分析 propofol 的血液动力学、呼吸的效果。方法：在这未来的研究，在三年的一个时期上进行了， 1,104 个病人参考了一一样的天官方补给的内视镜检查法过程被分析。所有病人被给一丸 propofol 大丸药(0.5-1.5 mg/kg ) 。动脉的血压(BP ) 在 3 min 间隔和心搏率被监视，氧饱和(SpO2 ) 被脉搏血氧定量法连续地记录。分析数据获得以前被执行，在期间，并且在过程以后。结果：在吝啬的动脉压的统计上重要的减小被表明(P 【
0.001 ) 什么时候与干预前价值，而是严重低血压相比，在 60 毫米汞柱下面定义为收缩血压，在仅仅 5 个病人(0.5%) 被注意。氧饱和从 96.5% ～ 94.4 % 减少了(P 【
0.001 ) 。在氧饱和的批评减少(【
90%) 在 27 个病人(2.4%) 被记录。结论：如果小心地滴定，我们的结果证明 propofol 向好镇静提供了优秀疼痛控制，短复原时间和没有重要血液动力学的副作用。所有病人(并且特别 ASA III 组) 要求监视并且一个麻醉学者关心。
AIM： To analyze the hemodynamic and respiratory effects of propofol on patients undergoing gastroscopy and colonoscopy. METHODS： In this prospective study, conducted over a period of three years, 1,104 patients referred for a same day GI endoscopy procedure were analyzed. All patients were given a propofol bolus （0.5-1.5 mg/kg）. Arterial blood pressure （BP） was monitored at 3 rain intervals and heart rate and oxygen saturation （SpO2） were recorded continuously by pulse oximetry. Analyzed data acquisition was carried out before, during, and after the procedure. RESULTS： A statistically significant reduction in mean arterial pressure was demonstrated （P〈0.001） when compared to pre-intervention values, but severe hypotension, defined as a systolic blood pressure below 60mmHg, was noted in only 5 patients （0.5%）. Oxygen saturation decreased from 96.5% to 94.4 % （P〈0.001）. A critical decrease in oxygen saturation （〈90%） was documented in 27 patients （2.4%）. CONCLUSION： Our results showed that propofol provided good sedation with excellent pain control, a short recovery time and no significant hemodynamic side effelts if carefully titrated. All the patients （and especially ASA Ⅲ group） require monitoring and care of an anesthesiologist.
基金
Supported by "Bates" Clinic, Svetice 15, Zagreb, Croatia, in the form of grant, equipment and drugs
