摘要
瞄准:检验参与胰腺并且在有自体免疫的胰腺炎的病人的胆汁管。方法:临床并且有自体免疫的胰腺炎的 28 个病人的 cholangiopancreatographic 调查结果被评估。为这研究的目的,胰腺的管系统被划分成三部分:腹的胰腺的管;背面的胰腺的管的头部分;并且背面的胰腺的管的身体和尾巴。结果:两个都,腹、背面的胰腺的管涉及 24 个病人,当在 4 个病人仅仅背面的胰腺的管涉及时。胆汁管的显著苛评在 20 个病人被检测,他们的起始的症状是妨碍的黄疸。六个病人显示出中等狭窄到正常直径的 30%-40% ,并且另外的二个病人没显示出胆汁管的狭窄。尽管胆汁管的显著苛评在 83% 被检测(20/24 ) 两个给看了的病人缩小腹、背面的胰腺的管,它没在独自看了背面的胰腺的管的参与的 4 个病人(P=0.0034 ) 被观察。结论:两腹、背面胰腺并且胆汁管与自体免疫的胰腺炎涉及病人。
AIM:To examine the involvement of the pancreatic and bile ducts in patients with autoimmune pancreatitis.
METHODS: Clinical and cholangiopancreatographic findings of 28 patients with autoimmune pancreatitis were evaluated. For the purposes of this study, the pancreatic duct system was divided into three portions: the ventral pancreatic duct, the head portion of the dorsal pancreatic duct; and the body and tail of the dorsal pancreatic duct.
RESULTS: Both the ventral and dorsal pancreatic ducts were involved in 24 patients, while in 4 patients only the dorsal pancreatic duct was involved. Marked stricture of the bile duct was detected in 20 patients and their initial symptom was obstructive jaundice. Six patients showed moderate stenosis to 30%-40% of the normal diameter, and the other two patients showed no stenosis of the bile duct. Although marked stricture of the bile duct was detected in 83% (20/24) of patients who showed narrowing of both the ventral and dorsal pancreatic ducts, it was not observed in the 4 patients who showed involvement of the dorsal pancreatic duct alone (P = 0.0034).
CONCLUSION: Both the ventral and dorsal pancreatic and bile ducts are involved in patients with autoimmune pancreatitis.
基金
Supported by Health and Labor Sciences Research Grants,Research on Specific Diseases(Intractable Diseases of the Pancreas)
关键词
胰腺疾病
胆导管
自体免疫
病理机制
Autoimmune pancreatitis
Dorsal pancreatic duct
Ventral pancreatic duct