摘要
有丙肝病毒(HCV ) 的感染的结果在个人之中从自我限制的感染实质地变化到长期的肝炎,肝肝硬化,和肝细胞癌。决定清理或 HCV 的坚持还没被澄清了的机制。这里,我们从一样的起源,但是与相当不同的结果与 HCV 经历了医院相关的感染的二个盒子。一个盒子在尖锐肝炎的一个事件以后解决了,当尽管他们感染一样的起源的 HCV,另外的盒子开发了长期的肝炎时。尽管与一样的起源的病毒感染了,临床并且 virological 功课是完全不同的。这建议主人因素在调节起一个主要作用尖锐 HCV 感染的结果。
The outcome of infection with hepatitis C virus (HCV) varies substantially from self-limiting infection to chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma among the individuals. The mechanisms that determine the clearance or the persistence of HCV have not yet been clarified. Here, we experienced two cases of hospital-related infection with HCV from the same origin but with quite different outcomes. One case resolved after an episode of acute hepatitis, while the other case developed a chronic hepatitis although they were infected with HCV of the same origin. Although infected with the virus of the same origin, the clinical and virological courses were completely different. This suggests that host factors play a major role in conditioning the outcome of acute HCV infection.