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Relationship between the Contents of MDA, the Activity of SOD in Serum of the Milk Goat with Fluorosis and the Erythrocytic Membrane Liquidity 被引量:1

Relationship between the Contents of MDA, the Activity of SOD in Serum of the Milk Goat with Fluorosis and the Erythrocytic Membrane Liquidity
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摘要 To research the relation among the erythrocytic membrane.liquidity and the contents of MDA, the activity of SOD in serum of the milk goat with fluorosis. An animal model with fluorosis was constructed, and the fluorescent probe technique of DPH was used to measue the erythrocytic membrane liquidity. At the same time, the contents of MDA and the activity of SOD in serum were measured. The results showed that the erythrocytic membrane liquidity in the control group and flurosis group were 5.6742 ± 0.4417 and 3.7248 ± 0.4521 (P 〈0.01) respectively, the contents of MDA in serum were 2.0408 ± 0.198 and 4.494± 0.438 (P 〈0.01) respectively, the activities of SOD were 175.638 ± 22.201 and 113.714 ± 34.258 (P 〈0.01) respectively. The correlation analysis indicated that the relation between the activity of SOD and the liquidity of erythrocytic membrane was positive correlation ( r= 0.7321, P 〈0.05), whereas the relation between the contents of MDA and the liquidity of erythrocytic membrane was negative correlation (r = -0.6438, P 〈0.01). The erythrocytic membrane liquidity decreased in milk goat with fluorosis, which played a role in the occurrence and development of the fluorosis. There was correlation among the erythrocytic membrane liquidity and the contents of MDA, the activity of SOD. To research the relation among the erythrocytic membrane.liquidity and the contents of MDA, the activity of SOD in serum of the milk goat with fluorosis. An animal model with fluorosis was constructed, and the fluorescent probe technique of DPH was used to measue the erythrocytic membrane liquidity. At the same time, the contents of MDA and the activity of SOD in serum were measured. The results showed that the erythrocytic membrane liquidity in the control group and flurosis group were 5.6742 ± 0.4417 and 3.7248 ± 0.4521 (P 〈0.01) respectively, the contents of MDA in serum were 2.0408 ± 0.198 and 4.494± 0.438 (P 〈0.01) respectively, the activities of SOD were 175.638 ± 22.201 and 113.714 ± 34.258 (P 〈0.01) respectively. The correlation analysis indicated that the relation between the activity of SOD and the liquidity of erythrocytic membrane was positive correlation ( r= 0.7321, P 〈0.05), whereas the relation between the contents of MDA and the liquidity of erythrocytic membrane was negative correlation (r = -0.6438, P 〈0.01). The erythrocytic membrane liquidity decreased in milk goat with fluorosis, which played a role in the occurrence and development of the fluorosis. There was correlation among the erythrocytic membrane liquidity and the contents of MDA, the activity of SOD.
出处 《Journal of Northeast Agricultural University(English Edition)》 CAS 2005年第2期118-121,共4页 东北农业大学学报(英文版)
关键词 milk goat FLUOROSIS erythrocytic membrane milk goat fluorosis erythrocytic membrane
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  • 1傅一工,生物物理学报,1985年,1卷,181页

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