摘要
端粒结合蛋白是指能够与端粒DNA特异序列结合的蛋白质及其调节蛋白,近年来端粒分子生物学的研究表明,端粒结合蛋白在维持端粒结构、保护染色体末端、调节端粒长度和端粒沉默以及细胞分裂、凋亡、永生化、癌变等方面起着广泛而重要的作用。
出处
《生物学教学》
北大核心
2006年第3期4-6,共3页
Biology Teaching
参考文献11
-
1Blackburn EH,Gall J.1978.A tandomly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena.Molecular Biology,120(1):33 ～53
-
2Greider CW,Blackburn EH.1985.Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.cell,43(12):405 ～413
-
3Gottsching DE,Cech TR.1984.Chromatin structure of the molecular ends of Oxytricha Macronuclear DNA:Phased nucleosomer and a telomic complex.Cell,38(2):501 ～510
-
4Shore D,Nasmyth K.1987.Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements.Cell,51 (5):721 ～732
-
5Cibrad MN,Wright JH,Wolf AJ,et al.1990.RAP1 protein interacts with yeast telomeres in vivo:overproduction alters telomere structure and decreases chromosome stability.Cell,63(4):739 ～ 750
-
6Hofmann JF-X,Caroche T.1989.RAP1 factor is necessary for DNA loop formation in vitro at silent mating type locus HML.Cell,57 (5):725 ～ 737
-
7Moretti P,Freeman K.1994.Evidence that a complex of SIR proteins interacts with the silencer and telomere-binding protein RAP1.Genes & Development,8 (19):2257 ～ 2269
-
8Van-Steensel B,de-lang T.1997.Control of telomere length by the human telomeric protein TRF1.Nature,385 (6618):740 ～ 743
-
9Griffith JD,Comeaul L,Rosenfields S,et al.1999.Mammalian telomemres end in a large duplex loop.Cell,97(4):503 ～504
-
10Smith S,Giriat I,Schmitt A,et al.1998.Tankyrase,a poly(ADP-ribose) polymerase at telomeres.Science,282 (5393):1484 ～1487
同被引文献28
-
1朱雅新,麻浩.端粒和端粒酶的结构与功能及其应用[J].湖南农业大学学报（自然科学版）,2005,31(1):98-105. 被引量：11
-
2李卫国,王坤英.端粒保护蛋白[J].细胞生物学杂志,2005,27(5):501-504. 被引量：1
-
3BlackburnDH, GalIJG. Atandemly repeated sequenc eat the termini of the extrach romosomal RNA genesinTetrahymena. JMolBiol, 1978, 120:33.
-
4HendersonE, HardinCC, WolkSK, etal. Telomeric DNA oligonucleotidesformnovelintramolecularstructurescontaining guanine, guaninebasepairs. Cell, 1987,51:899.
-
5GottschingDE, CechTR. 1984. Chromatinstructureofthemolecu - larendsof OxytrichaMacronuclear DNA : Phasednucleosomerandatelomiccomplex. Cel, 138 (2) :501 - 510.
-
6BaumannP, ThomasRC. 2001. POT1, theputativeTelmereendbindingproteininfissionyeastandhuman. Science,292 ( 5519 ) : 1171 - 1175.
-
7ShoreD, NasmythK. 1987. PurificationandcloningofaDNAbind - ingproteinfromyeastthatbindstobothsilencerandactivatorele - ments. Cel, 151 (5) :721 -732.
-
8CibradMN, WrightJH, WolfAJ, eta. 11990. RAP1 proteininteractwithyeasttelomeresinvivo: over productional terstelomerestructuranddecreaseschromosomestability. Cel, 163 (4) :739 - 750.
-
9Van - SteenselB, de - langT. 1997. ControIof telomere length b the human telomericprotelnTRF1. Nature,385 (6618 ) :740 - 743.
-
10GriffithJD, ComeaulL, RosenfieldsS, eta. 11999. Mare maliant lomem resendinalargeduplexloop. Cel, 197 (4) :503 - 504.
二级引证文献2
-
1张瑞,张天留,宋美华,徐凌洋,高会江,李俊雅,陈燕,高雪.重复序列在牛亚科中的研究进展[J].中国畜牧杂志,2021,57(4):33-38. 被引量：3
-
2张瑞,马钧,陈燕,张天留,范婷婷,朱波,张路培,徐凌洋,高会江,李俊雅,高雪.牛亚科物种TRs分布特点及着丝粒区卫星DNA进化研究[J].畜牧兽医学报,2021,52(10):2792-2802.
-
1范玉贞.端粒结合蛋白与端粒长度的调节机制[J].生物学教学,2002,27(7):3-4.
-
2任建国,周军,戴尧仁.端粒及端粒酶的研究进展[J].生物化学与生物物理进展,1999,26(5):415-415. 被引量：14
-
3唐双焱,邹国林.端粒酶·端粒序列·端粒结合蛋白[J].氨基酸和生物资源,1997,19(1):47-51.
-
4汤立旦,黄河,詹金彪.Tankyrase——一种多功能的端粒结合蛋白[J].国外医学（临床生物化学与检验学分册）,2005,26(1):18-20.
-
5江红,郑晓飞,罗瑛,朱捷,付汉江,孙强玲,陈长浩,孙志贤.人端粒结合蛋白TRF1的克隆、表达和抗体制备[J].生物工程学报,2004,20(1):30-33. 被引量：3
-
6王渭霞,刘小川,朱廷恒.高等植物端粒和端粒酶的研究进展[J].遗传,2003,25(1):113-118. 被引量：3
-
7Won Kyung Lee,Ji-Hye Yun,Weontae Lee,Myeon Haeng Cho.DNA-Binding Domain of AtTRB2 Reveals Unique Features of a Single Myb Histone Protein Family that Binds to Both Arabidopsis- and Human-Type Telomeric DNA Sequences[J].Molecular Plant,2012,5(6):1406-1408.
-
8梁铮铮,胡剑.端粒、端粒酶结构功能研究进展[J].生物技术通讯,2003,14(4):312-315. 被引量：3
-
9杨雪莲,陶茂萱.端粒、端粒酶系统的调控与研究现状[J].卫生研究,2004,33(3):369-371. 被引量：2
-
10陈耿,周建新,董燕麟.端粒结合蛋白与端粒长度调控[J].生物化学与生物物理进展,1999,26(5):419-422. 被引量：2
