摘要
目的研究烧伤创面应用无水磺胺嘧啶锌后血锌和尿锌的含量变化。方法取烧伤患者浅Ⅱ度创面,用无水磺胺嘧啶锌粉剂1.0g撒于1%烧伤面积创面上,连续3d,1次/d,分别于用药前、用药后3d、用药后1wk测定血锌和24h尿锌含量。结果与用药前比较,用药后血锌含量无显著性变化(P>0.05),尿锌含量显著升高(P<0.01)。结论无水磺胺嘧啶锌应用于烧伤创面后,锌吸收量少,体内锌离子主要通过肾脏排泄。
OBJECTIVE：To study the serum and urine zinc level changes after applying anhydro- sulfadiazine zinc in burn wound. METHODS： 1.0g ram of anhydro-sulfadiazine zinc powder was applied to 1% body surface area of burn wound once daily for 3 consecutive days.Serum zinc level and 24hs urine zinc level were detected respectively before medication, 3 days and 1 week after medlcatlon.RESULTS： No significant change was found in serum zinc level after medication as against before treatment（P〉 0.05）, but the 24h urine zinc level increased markedly（P〈0.01） .CONCLUSION： After applying anhydro- sulfadiazinc zinc in burn wound,little dose of zinc can be absorbed and the in vivo zinc ions are chiefly excreted through kidney.
出处
《中国药房》
CAS
CSCD
北大核心
2006年第5期368-369,共2页
China Pharmacy
关键词
无水磺胺嘧啶锌
烧伤创面
锌含量
Anhydro - sulfadiazine zinc
Burn wound
Zinc level
