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内皮素及其受体与肾损害的研究进展 被引量:1

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摘要 内皮素(ET)是一种合成于内皮细胞粗面内质网的多肽,与特定受体(ETR)结合后通过一系列的信息传递而发挥强烈的生物效应。肾组织能合成和分泌成熟的ET,同时也有规律地分布ETR。肾功能与ET的关系密切,血液、尿液中ET的变化不同程度反映了肾脏损害和修复的过程。目前,相关研究的热点集中于不同类型肾损害中ET改变的内在机制及临床意义。
出处 《江苏医药》 CAS CSCD 北大核心 2006年第3期255-256,共2页 Jiangsu Medical Journal
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