摘要
目的:探讨可注射硫酸钙在椎弓根螺钉固定中的作用。方法:取16个新鲜猪腰椎标本,随机分为两组,每组8个。第1组在双侧椎弓根丝锥攻丝,一侧钉道内填充可注射硫酸钙MIIGX3(minimally invasive injectable graftX3)(1A组),另一侧作为自身对照(1B组),拧入椎弓根钉后1h行拔出实验。第2组同样双侧攻丝,一侧填充MIIGX3(2A组),另一侧自身对照(2B组),拧入椎弓根钉后24h行拔出实验。比较填充MIIGX3与不填充以及填充1h与填充24h的最大轴向拔出力有无差别。结果:1A组最大轴向拔出力为1837.5±251.7N,1B组为1003.8±85.0N,2A组为1895.0±252.5N,2B组为1027.5±97.8N。对4组数据作析因设计的方差分析,填充MIIGX3与不填充比较,即1A组与1B和2A组与2B组比较,存在显著性差异(P<0.001);填充1h与填充24h比较,即1Avs2A,无显著性差异(P>0.05)。结论:MIIGX3对椎弓根钉的固定有明显的增强作用,且填充1h与填充24h固定强度无差异。
Objective:To evaluate the biomechanical effect of injectable calcium sulfate-based bone graft substitute (MIIGX3) on strengthening pedicle screw fixation.Method:16 fresh pig lumbar vertebrae were randomly and evenly divided into two groups(group 1 and group 2).A track was made in each vertebral pedicle with a tap,and MIIGX3 was injected into one track of each vertebra (A side),leaving the contralateral track as control(B side ).Pullout test was performed at 1 hour after fixation in group 1 ,while at 24 hours after fixation in group 2.Result:Maximum axial pullout strength was 1837.5±251.7N in group IA,1003.8±85.0N in group IB,1895.0±252.5N in 2A,and 1027.5±97.8N in 2B.There was significant difference between IA and IB (P〈0.001) ,also between 2A and 2B(P〈0.001).But there was no significant difference between IA and 2A(P〉0.05).Condusion:Injectable calcium sulfate-based bone graft substitute MIIGX3 can significantly strengthen pedicle screw fixation.
出处
《中国脊柱脊髓杂志》
CAS
CSCD
2006年第2期152-154,共3页
Chinese Journal of Spine and Spinal Cord
关键词
椎弓根钉
可注射硫酸钙
腰椎
生物力学
Pedicle screw
Injectable calcium sulfate
Lumbar vertebra
Biomechanics