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PET/CT模拟定位系统在放射治疗中的初步应用 被引量：11

PET/CT simulation and treatment planning system for radiation therapy
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摘要 目的:评价PET/CT模拟定位系统在放射治疗中的作用。方法:将PET/CT、三维激光定位系统和Focus3.2.1三维计划系统通过网络连接,形成放疗科专用的三维PET/CT模拟定位计划系统,分别对62例肿瘤患者进行PET/CT模拟定位和治疗计划。结果:通过改造组成的PET/CT模拟定位系统,比CT模拟定位提供更丰富和准确的图像信息,指导靶区GTV的勾画和放疗效果的评价。结论:PET/CT模拟定位系统明显提高放疗的定位精度,是未来放疗治疗定位的发展趋势。 Objective：To evaluate the value of 3D PET/CT simulation and treatment planning system （3D PET/CT-Sim） in high precise radiotherapy. Methods.A radiotherapy-oriented 3D PET/CT-Sim consists of a Discovery LS16 PET/CT, a laser alignment system and Focus Dusimulator was installed in our hospital. From Feb04 to Oct04, PET/CT simulation and treatment planning of 62 patients were performed on this system. The simulation and planning process included patient positioning,laser alignment, PET/CT scanning, imaging transferring, and treatment planning. Results： PET/CT might more accurately provide the useful fusion images to the physician as the whole process from gross tumors volume（GTV） delineation to evaluation effects after radiotherapy than the CT-simulator. Conclusion：The precise of PET/CT simulation is higher than CT simulation. 3D PET/CT-Sim would make much contribution to the radiotherapy in the future.
作者 傅志超 程惠华 原锦 赖红斌 李东石 林贵山 陈建英
机构地区 南京军区福州总医院放疗科
出处 《临床肿瘤学杂志》 CAS 2006年第2期120-122,132,共4页 Chinese Clinical Oncology
关键词 正电子发射体层显像 计算机体层摄影 放射疗法 立体定位技术 Positron emission tomography Computed tomography Radiotherapy Stereotaxic techniques
分类号 R815 [医药卫生—放射医学] R814.42 [医药卫生—影像医学与核医学]
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参考文献9

  • 1Ciernik IF,Dizendorf E,Baumert BG,et al.Radiation treatment planning with an integrated positron emission and computer tomography(PET/CT):a feasibility study C[J].Int J Radiat Oncol Biol Phys,2003,57 (3):853-863.
  • 2Balogh JB,Caldwell CB,Ung YC,et al.interobserver variation in contouring gross tumor volume in carcinoma of the lung associated with pneumonitis and atelectasis:the impact of 18 FDG-hybrid pet fusion[J].Int J Radiat Oncol Phys,2000,48 (5):128-129.
  • 3Caldwell CB,Mah K,Ung YC,et al.Observer variation in contouring gross tumor volume in patients with poorly defined nonsmall-cell lung tumors on CT:the impact of 18FDG-hybrid PET fusion[J].Int J Radiat Oncol Biol Phys,2001,51 (4):923-931.
  • 4Ciernik IF,Dizendorf E,Baumert BG,et al.Radiation treatment planning with an integrated positron emission and computer tomography (PET/CT):a feasibility study[J].Int J Radiat Oncol Biol Phys,2003,57 (3):853-863.
  • 5Schwartz DL,Ford E,Rajendran J,et al.FDG-PET/CT imaging for preradiotherapy staging of head-and -neck squamous cell carcinoma[J].Int J Radiat Oncol Biol Phys,2005,61 (1):129-136.
  • 6Rizzo G,Cattaneo GM,Castellone P,et al.Multi-modal medical image integration to optimize radiotherapy planning in lung cancer treatment[J].Ann Biomed Eng.2004,32 (10):1399-1408.
  • 7于金明,邢力刚,杨国仁.^(18)F-脱氧葡萄糖PET用于制定肿瘤放射治疗计划研究进展[J].中华放射肿瘤学杂志,2004,13(2):133-136. 被引量：20
  • 8林祥通.国内正电子发射断层(PET)现状和展望[J].核技术,2003,26(5):353-357. 被引量：15
  • 9Mutic S,Dempsey JF,Bosch WR,et al.Multimodality image registration quality assurance for conformal three-dimensional treatment planning[J].Int J Radiat Oncol Biol Phys,2001,51 (1):255-260.

二级参考文献23

  • 1赵军,林祥通,管一晖,左传涛,华逢春,陆舜.结核病^(18)F-FDG PET图像表现的多样性[J].中华核医学杂志,2003,23(S1):41-43. 被引量：44
  • 2Ling CC, Humm J, Larson S, et al. Towards multidimensional radiotherapy (MD-CRT): biological imaging and biological conformality.Int J Radiat Oncol Biol Phys, 2000,47:551-560.
  • 3Erdi YE, Rosenzweig K, Erdi AK, et al. Radiotherapy treatment planning for patients with non-small cell lung cancer using positron emission tomography (PET). Radiother Oncol, 2002,62: 51-60.
  • 4Kiffer JD, Berlangieri SU, Scott AM, et al. The contribution of 18F-fluoro-2-deoxy-glucose positron emission tomographic imaging to radiotherapy planning in lung cancer. Lung Cancer, 1998 , 19:167-177.
  • 5Nestle U, Walter K, Schmidt S, et al. 18F-deoxyglucose positron emission tomography (FDG-PET) for the planning of radiotherapy in lung cancer: high impact in patients with atelectasis. Int J Radiat Oncol Biol Phys, 1999,44:593-597.
  • 6Munley MT, Marks LB, Scaffone C, et al. Multimodality nuclear medicine imaging in three-dimensional radiation treatment planning for lung cancer: challenges and prospects. Lung Cancer, 1999, 23: 105-114.
  • 7Graud P, Grahek D, Montravers F, et al. CT and 18F-deoxyglucose (FDG) image fusion for optimizations of conformal radiotherapy of lung cancers. Int J Radiat Oncol Biol Phys, 2001,49:1249-1257.
  • 8Mah K, Caldwell CB, Ung YC, et al. The impact of (18)FDG-PET on target and critical organs in CT-based treatment planning of patients with poorly defined non-small-cell lung carcinoma: a prospective study. Int J Radiat Oncol Biol Phys, 2002,52: 339-350.
  • 9Schmuecking M, Plichta K, Lopatta EC, et al. Image fusion of 18FDG PET and CT, is there a role in 3D-radiation treatment planning of nonsmall cell lung cancer? Int J Radiat Oncol Biol Phys, 2000, 48 Suppl:130.
  • 10Caldwell CB, Mah K, Ung YC, et al. Observer variation in contouring gross tumor volume in patients with poorly defined non-small-cell lung tumors of CT: the impact of 18FDG-hybrid PET fusion. Int J Radiat Oncol Biol Phys, 2001,51:923-931.

共引文献33

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引证文献11

二级引证文献52

临床肿瘤学杂志
2006年 第2期

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