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小动物PET在药物研究中的应用 被引量：5

The application of small animal PET in drug development
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摘要 小动物PET是一种定量显像技术,能够无创伤地、动态地显像正电子核素标记的放射性药物在活体内的分布,为药物研究和评价提供了一个新的研究方法和途径。这篇文章主要介绍了小动物PET的一些基本知识及其在药物开发和研究中的应用。 Small animal PET is a quantitative imaging technique that can noninvasive and dynamically image the distribution of positron-labeled radiopharmaceuticals in vivo, therefore representing a new means of providing information for drug development and evaluation. This article reviews the fundamental basis of PET imaging and their application in preclinical drug discovery and development.
作者 方红娟 杜延荣 李方 陈方
机构地区 中国医学科学院.中国协和医科大学北京协和医院核医学科
出处 《中国药理学通报》 CAS CSCD 北大核心 2006年第3期270-273,共4页 Chinese Pharmacological Bulletin
关键词 小动物PET 分子显像 药物研究 small animal PET molecular imagine drug discovery and development
分类号 R-332 [医药卫生] R814.42 [医药卫生—影像医学与核医学]
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参考文献24

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二级参考文献27

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共引文献5

同被引文献35

引证文献5

二级引证文献6

中国药理学通报
2006年 第3期

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