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硒与皮肤病 被引量:2

Selenium and Skin Diseases
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摘要 微量元素硒是机体重要的抗氧化酶谷胱甘肽过氧化物酶的必需组分,具有广泛的生物学功能, 尤其在抗氧化、免疫调节、抗炎症、抗肿瘤、抗衰老等方面,已引起人们的关注。研究表明,硒与一些皮肤病的发生、发展密切相关。为此,就硒与银屑病、白癜风、紫外线照射对皮肤损伤及皮肤肿瘤的发生、发展及转归中的生物学作用等方面的研究进展进行综述。 Selenium (Se) is an essential trace element for animals and humans because of its role in glutathione peroxidase (GSH-Px), an antioxidant enzyme. It has many biological activities, such as antioxidant, immunomodulatory, anti-inflammatory, anticarcinogenic, anti-aging and so on. Recently, increasing evidence has demonstrated that selenium is closely related to the occurence and development of skin diseases, and has a therapeutic effect on these diseases. This paper focuses on the biological functions of selenium and selenium compounds in the development, treatment and prognosis of psoriasis, vitiligo, skin damage by ultraviolet, cutaneous tumors and so on.
作者 冀然 蒋献
出处 《国际皮肤性病学杂志》 2006年第2期111-113,共3页 International Journal of Dermatology and Venereology
关键词 皮肤疾病 Selenium Skin diseases
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  • 1Chung-Yung Jetty Lee,Jennifer Man-Fan Wan.Immunoregulatory and antioxidant performance of α-tocopherol and selenium on human lymphocytes[J].Biological Trace Element Research.2002(2)
  • 2V. I. Reshetnyak,T. I. Sharafanova,L. Yu. Il’chenko,G. G. Poroshenko.DNA Structure in Peripheral Blood Lymphocytes from Patients with Chronic Viral Liver Damages[J].Bulletin of Experimental Biology and Medicine.2002(4)
  • 3C. Loguercio,V. Girolamo,A. Federico,S. L. Feng,E. Crafa,V. Cataldi,G. Gialanella,R. Moro,C. Vecchio Blanco.Relationship of blood trace elements to liver damage, Nutritional status, and oxidative stress in chronic nonalcoholic liver disease[J].Biological Trace Element Research.2001(3)

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