红药化学成分的研究

Studies on the chemical constituents from stem of Chirita longgangensis var.hongyao

目的:分离鉴定红药干燥茎的化学成分。方法:甲醇提取,硅胶、Sephadex LH-20及ODS柱色谱分离,采用NMR和MS等方法确定化合物的结构。结果:分离鉴定了7个化合物,分别为2-hydroxy-7-methyl-9,10-an-thraquinone(1),2-methyl-9,10-anthraquinone(tectoquinone)(2),乌苏酸(3),香草酸(4),-βsitosteryl-D-glucoside-6’-palmitate(5),β-谷甾醇(6),胡萝卜苷(7)。结论:化合物1,2,3,5为首次从该科植物中得到,化合物4,6为首次从该属植物中得到,化合物7为首次从该植物中得到。

Objective： To isolate and elucidate the constituents from stem of Chirita longgangensis var. hongyao. Method： The constituents were extracted with methanol and isolated by chromatography on silica gel, Sephadex LH-20 and ODS. The structures were determined by NMR and MS spectral analysis. Result： Seven compounds were identified as 2-hydroxy-7-methyl-9, lO-anthraquinone （1）, 2-methyl-9, 10-anthraquinone （tectoquinone） （2）, ursolic acid （3）, vanillic acid （4）, β-sitosteryl-D-glucoside-6＇-palmitate （5）, β-sitosterol （6）, daucosterol （7）, respectively. Conclusion： Compounds 1, 2, 3 and 5 were isolated for the first time from the family Gesneriaceae, compounds 4 and 6 were isolated for the first time from the genus Chirita, and compound 7 was isolated for the frist time from Chhirita longgangensis var.