甘精胰岛素治疗对糖尿病患者生活质量的影响

The effect of insulin glargine on the quality of life in diabetics

糖尿病不仅给患者带来巨大的健康负担,还会严重影响患者的生活质量。糖尿病治疗的主要目的是为了降低糖尿病患者并发症的发生率和死亡率,但是在治疗过程中可能引起患者生活质量的下降。甘精胰岛素是胰岛素的类似物,可以使患者在获得较好血糖控制的同时较少发生低血糖反应。研究显示与中效胰岛素(NPH)或者一些其他1型糖尿病常用胰岛素治疗方案相比,甘精胰岛素的治疗可以改善1型和2型糖尿病患者的治疗满意度、总体情感和健康感觉。在口服降糖制剂的基础上加用甘精胰岛素可提高治疗满意度。

Diabetes mellitus not only brings heavy health burden to patients, but also impairs their quality of life. The treatment of diabetes aims to lower the morbidity and mortality of diabetic complications of patients, but may decrease the short-term quality of life. Insulin glargine is an insulin analogue which has better glucose control and less hypoglycemic episodes. Studies in type 1 diabetes found that, compared to NPH insulin or other conventional insulin therapy for type 1 diabetes, treatment with insulin glargine can improve the treatment satisfaction, total emotional well-being and total health well-being. Adding insulin glargine to oral antihyperglycemic agents can improve the treatment satisfaction.