新型1-芳氧基-4-氯酞嗪的合成及除草活性

Syntheses and Herbicidal Activities of Novel 1-Aryloxy-4-Chloro Phthalazines

由1,4-二氯酞嗪与多种取代苯酚在DMF中缩合,合成了一系列1-芳氧基-4-氯酞嗪类化合物。所有化合物均经1H NMR和元素分析确证,部分化合物经IR确证。初步的生物活性研究表明,该类化合物具有一定的除草活性。

A series of 1-aryloxy-4-chloro phthalazines （3） was prepared in DMF with a high yield from the condensation reaction of substituted phenols with 1,4-dichloro phthalazine, which was obtained from the chlorination of 1,4-phthalazin-dione by PCl5/POCl3. These novel compounds were characterized by means of ^1H NMR and elemental analyses and some of them were confirmed by IR. Preliminary bioassay indicates that some of above compounds show a certain herbicidal activity against Brassica napus and Echinochloa Crusgalli at 0. 01 g/L.