钛基SiO_2薄膜的制备及生物活性

Preparation and Bioactivity of Silica Films Coated on Titanium

采用溶胶-凝胶（Sol-Gel）工艺在金属钛基底上制备SiO2薄膜。探讨了工艺条件对SiO2薄膜质量的影响。用X射线衍射（XRD）、红外光谱（FTIR）和扫描电镜（SEM）等测试技术对薄膜的表面组成、结构与形貌进行了研究。结果表明，当控制溶胶pH=3，n（TEOS）：n（H2O）：n（EtOH）=1：4：11时，在70℃下陈化10h可获得粘性适宜的溶胶，所镀的SiO2薄膜不发生龟裂，表面均匀多孔，孔径分布在2—3μm之间。所制备的SiO2薄膜在1．5倍模拟体液中浸泡10d后其表面迅速形成由球状碳磷灰石（CHA）颗粒组成的沉积层，说明SiO2薄膜具有良好的生物活性。

Silica films were prepared on titanium substrate by a sol-gel method. The influence of different factors on the quality of silica films is discussed in this paper. The surface composition, microstructure and surface morphology of the films were characterized by X-ray diffraction （ XRD）, fourier transform infrared spectrometry （FTIR） and scanning electron microscopy （SEM）, respectively. The results show that the sol prepared at pH 3 and a n（TEOS）：n（ H2O）：n（EtOH） ratio of 1：4：11 and aged for 10 h at 70 ℃ was suitable for plating silica films on titanium substrate. The silica films were crackfree, uniform and porous. The pore size distributions was between 2 and 3 μm. After immersing the silica films in simulated body fluid（1.5SBF） for 10 d, the rapid depositon of spherical carbonated hydroxyapatite（CHA） on the surface of the films showed that the bioactivity of silica films was very good.