细胞色素C与脑缺血神经元迟发性死亡

下载PDF

导出

作者刘超陈建国

机构地区华中科技大学同济医学院药理系

出处《咸宁学院学报（医学版）》 2006年第1期1-5,共5页 Journal of Xianning Univarsity(medical Sciences)

基金国家自然科学基金资助项目[30570556]

关键词脑缺血损伤迟发性死亡缺血神经元细胞色素C 细胞凋亡 DNA片段化细胞死亡缺血中心区缺血半暗区啮齿类动物

参考文献30

1Choi DW.Ischemia induced neuronal apoptosis[J].Curr Opin Neurobiol,1996,6(5):667
2Green DR,Reed JC.Mitochondria and apoptosis[J].Science,1998,281:1309
3Armstrong JS,Steinauser KK,French J,et al.Bcl-2 inhibits apoptosis induced by mitochindrial uncopling but does not prevent mitochondrial transmembraned epilarization[J].Exp Cell Res,2000,262:120
4Camilleri BS,Vanderwerff H,Caldwell E,et al.Distinct alterations in mitochondrial mass and function characterize different models of apoptotsis[J].Exp Cell Res,1998,239(2):277
5Greend,Kroemer G.The central executioners of apoptosis:caspases or mitochondria[J].Trends Cell Biol,1998,8:267
6Yang J,Liu X,Bhalla K,et al.Prevention of apoptosis by Bcl-2:release of cytochrome c from mitochondria blocked[J].Science,1997,275(5303):1129
7Hansson MJ,Persson T,Friberg H.Powerful cyclosporin inhibition of calcium-induced permeability transition in brain mitochondria[J].Brain Research,2003,960(1-2):99
8Jurgensmeier JM,Xie Z,Deveraux Q,et al.Bax directly induces release of cytochrome c from isolated mitochondria[J].Proc Natl Acad Sci USA,1998,95(9):4997
9Wigdal SS,Kirkland RA,Franklin J,et al.Cytochrome C release precedes mitochondrial membrane potential loss in cerebellar granule neuron apoptosis:lack of mitochondrial swelling[J].Journal of Neurochemistry,2002,82(5):1029
10Kluck RM,Bossy-Wetzel E,Green DR,et al.Injected cytochrome c induces apoptosis[J].Nature,1998,391(6666):449

咸宁学院学报（医学版）

2006年第1期

内容加载中请稍等...