创伤失血性休克后机体反应的性别二态性

Divergent responses in gender after trauma-hemorrhagic shock

大量的临床及实验数据证明，在正常及病理条件下，机体在很多方面的反应都存在着性别二态性，但国内在这一领域的研究很少。本文着重将近年来国外有关雄性和雌性在创伤失血性休克后免疫功能、器官功能以及多形核白细胞（PMN）启动和活化等方面不同的研究作一综述。并以此为根据介绍了一些可以应用于临床的治疗失血性休克的新方法。

Abundance of clinical and experimental data suggests, under both normal and pathophysiological conditions, the body has sexual dimorphism in many aspects. But domestic research reports in this area are few. In this article, the author summarized the status of recent studies in foreign countries on divergent responses in gender after trauma-hemorrhagic shock, especially in immune status, organ function, and the priming and activition of polymorphonuclear（PMN） cell. Based on this, some novel agent in trauma-hemorrhagic shock therapy were introduced.