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强直性脊柱炎病人应用益赛普治疗局部反应的临床观察 被引量:24

Clinical observation on local reaction of ankylosing spondylitis patients treated with etanercept
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摘要 [目的]观察强直性脊柱炎(AS)病人注射益赛普后注射部位的皮肤反应。[方法]对52例AS病人注射过程中和注射后进行随访观察,以发放问卷调查的形式对发生的不良反应进行追踪。[结果]52例共进行1248次注射,其中有13例(25.0%)共81次(8.7%)出现了注射部位皮肤反应(局部红、肿、硬结、痒),其中中度1例,轻度12例。[结论]应用益赛普治疗AS后注射部位皮肤反应较常见,但无需药物治疗,一般可自行缓解。 Objective: To observe the local skin reaction of ankylosing spondylitis (AS) patients after injected etanercept. Method: A total of 52 AS patients were followed up during and after injection, and adverse reaction of all patients were observed by filling out questionnaires. Result: Skin reaction of injection site happened 81 times (about 8.7% ) of 13 patients (25.0%) among totally 1 248 times of injection of 52 cases which manifested as local redness, swelling, sclerosis and itching. Of 12 cases were with slight reaction. Only one case was moderate reaction. Conclusion: Etanercept induced skin reaction of injection site is relative common. Most of them could relieved and no need medication.
出处 《护理研究(上旬版)》 2006年第3期610-612,共3页 Chinese Nursing Researsh
关键词 益赛普 强直性脊柱炎 注射部位 皮肤反应 etanercept ankylosing spondylitis injection site skin reaction
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