阿托伐他汀治疗脑梗死中运动捕捉与运动评估量表和Barthel指数疗效评价的比较

Comparison of Motion Capture and Motor Assessment in Evaluatint of Effect on Treatment of Patients with Cerebral Infarction with Atorvastatin

目的:运动捕捉(MoCA)分析脑梗死后肢体运动状态,探讨阿托伐他汀(立普妥)对脑梗死预后影响。方法:43例脑梗死患者分对照组和阿托伐他汀组。在急性期和3个月应用运动评估量表(MAS)及Barhel指数(BI)评分;MoCA分析肢体运动状态。结果:两组3个月时与急性期比较MAS、BI均增加(P<0.01),但组间无统计学差异;MoCA分析患侧与健侧肢体抬高高度差值的均数均减小,阿托伐他汀组明显,有统计学差异(P<0.05),但组间无统计学差异。结论:长期应用阿托伐他汀对脑梗死预后改善不明显,需进一步研究;MoCA是一种评估运动障碍程度的较好方法。

Aim： To analyze motion state of limbs after cerebral infarction with motion capture analysis system （MoCA） and discuss the effect of applying statins-related drug in acute stage on long-term prognosis of cerebral infarction. Methods： 43 cases with acute cerebral infarction were divided into control group and atorvastatin group by using random control method. The neurologic deficit scale with motor assessment scale and Barthel Index scoring method were performed in acute stage and 3 months after stroke, respectively. Motion function state was analyzed with MoCA. Results： There was a significant difference （P 〈 0.01） between acute stage with 3 months after episode of cerebral infarction in MAS and BI group, however, there was no difference between the two groups. MoCA could reflect objectively motion orbit of limbs joint and find the difference （uninjured side-injured side） of average of height bilateral limbs raise between acute stage and 3 months after stroke. Conclusion： Application of atorvastatin in long-term was not of apparent effect on prognosis of cerebral infarction, and the therapeutic effect of atorvastatin on acute cerebral infarction needed to be further studied. MoCA ~as a better approach to evaluate the degree of motion disorder.