斜坡脊索瘤的手术治疗(47例分析)

The Surgical Treatment of 47 Case of Clival Chordoma

目的:斜坡脊索瘤的临床特点和手术方法分析。方法:对自1994年1月-2003年6月在本院接受手术治疗的47例斜坡脊索瘤进行回顾性分析。结果:47例患者发病年龄为5～67岁,平均39岁。男女比例约为1.47∶1。头痛、复视是本病最常见的症状。47例患者中,肿瘤全切16例,次全切除18例,部分切除13例。结论:目前斜坡脊索瘤手术全切率低,预后差,首次手术应尽可能达到全切。较彻底的手术切除和新型放射治疗的结合可能为斜坡脊索瘤的治疗带来新的希望。

Aim： To investigate the clinical characteristics and surgical approaches of clival chordoma. Methods： The clinical data of 47 patients with clival chordoma, treated from Jan.1994 to Jun.2003 in our department, were reviewed. Results： The patient age at diagnosis ranged from 5-67 years（ mean, 39 years ）. The male to female ratio was 1.47：1. Symptoms of headache and diploia were the main clinical manifestation. Radical, subtotal, and partial resections were achieved in 16, clival chordoma with low radical resection and poor outcome 18, 13 cases respectively. Conclusion： The is suitable for aggressive surgial treatment. Clival chordoma is best treated by aggressive initial surgical resection followed by newer modalifies of radiation therapy.