特发性脊髓萎缩症(附9例分析)

Idiopathic Amyelotrophy Disease

目的:探讨脊髓萎缩症的临床表现及磁共振成像(MRI)特征。方法:对9例脊髓萎缩症患者的临床表现及MRI检查资料进行回顾性分析。结果:颈、胸髓萎缩2例,胸髓萎缩7例,均表现为慢性起病,进行性加重的脊髓病变症状;痉挛性截瘫9例,感觉障碍5例,下肢腱反射活跃、亢进9例,病理征阳性7例,括约肌功能障碍3例;肌电图提示神经源性损害,MRI显示脊髓萎缩性改变9例;脊髓矢状径分别为3～5.5mm,脊髓矢状径与脊蛛网膜下隙矢状径比值<0.5。结论:脊髓萎缩症系脊髓慢性变性疾病,结合临床特征及MRI改变可作出较明确诊断。

Aim： To evaluate the clinical and imaging features of amyelotrophy disease. Methods： The clinical and MR imaging data of 9 cases of amyelotrophy disease were retrospectively studied. Results： Among 9 cases of amyelotrophy disease, cervical cord and thoracic cord analosis were found in 2 cases,thoracic cord analosis were found in 7 cases.The clinical manifestions were slow development and progressive aggravation, such as the symptoms of the myeleterosis. 9 cases had spastic paraplegia, active or sthenic inferior extremity tendon reflex, 5 cases had functional disturbance in musculus sphincter.EMG showed impaired nerves injury, MRI showed amyelotrophy change in 9 cases.The sagittal diameter of spinal cord were 3 -5.5 mm,the rate of sagittal diameter between spinal cord and subarachnoid was lower than 0.5. Conclusion： Amyelotrophy disease was a kind of chronic degenerative sickness,it could be made a definite diagnosis with clinic feature and MRI changes.