胰体尾癌外科治疗117例临床分析

Surgical therapy of tumor of body and tail of pancreas:report of 117 cases

目的探讨胰体尾癌的诊断、外科治疗方法和预后的影响因素。方法回顾性分析1996至2003年我院行手术探查并获病理诊断的117例胰体尾癌病例的临床病理资料。结果综合运用B超、CT、MR I与肿瘤标志物检测可于术前诊断95%以上病例,而根治性切除组与姑息性切除组和未切除肿瘤组中位生存时间分别为18、8和3.5个月。结论综合运用影像和血清学检查有利于较早诊断胰体尾癌;积极行手术切除肿瘤是胰体尾癌患者获得长期生存的惟一途径,而肿瘤的大小、对重要血管和邻近脏器的侵犯程度是影响肿瘤能否切除的重要因素。

Objective To explore diagnosis and surgery therapy and factors influencing the prognosis of tumor of body and tail of the pancreas. Methods The clinical deta of 117 cases of tumor of tail and body of pancreas who underwent operation were analysed. Results Imaging and tumor marker detection can give exact diagnosis to cases with tumors of body and tail of pancreas. The medial survival time of radical resection, palliative resection and exploratory laparotomy were 18, 8 and 3. 5 months.. Conclusions Atypical signs should be noticed, combined imaging and serum dectection can diagnose the cases exactly, radical resection is the unique method for long survival, the diameter of the tumor and degree of infiltration to maior vessels and organs is important.