1Reina JJ, Aparicio J, Salvador J, et al. A multicenter phase II study of irinotecan ( CPT-11 ) alternated with 5-fluorouracil and leucovorin as first-line treatment of patients with metastatic colorectal cancer[J]. Cancer Chem Pharm, 2003, 52 (4):339-345.
2Toumigand C, Andre T, Achille E, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study [ J ]. J Clin Oncol, 2004, 22 ( 2 ) :229 - 237.
2Tournigand C, Andre T, Achille E, et al. FOLFIR Ⅰ followed by FOLFOX 6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol, 2004, 22: 229-237.
3Rothenberg ML.Efficacy and toxicity of irinotecan in patients with colorectal cancer[J].Semin Oncol,1998,25(5Suppl 11):39-46.
4Saltz LB,Cor JV,BlankeC,et al.Irinotecan stuady group:irinotecan plus fluorourcil and leucovorin for metastasis colorectal cancer[J].N Engl Jmed,2000,343(13):905-914.
5周继昌.实用肿瘤内科学[M]北京:人民卫生出版社,200328-3045-47.
6de Gramont A,Bosset JF,Milan C. Randomized trial comparing monthly low-dose leueovorin and fluorouracil bolUS with bimonthly high-dose leucovorin and fluoreuracil bolus plus continuous infusion for advanced colorectal cancer:a French intergroup study[J].Journal of Clinical Oncology,1997,(02):808-815.
7Rothenberg ML. Efficacy of oxaliplatin in the treatment of colorectal cancer[J].Oncology(Huntington),2000,(z12):9.
8de Gramont A,Banzi M,Navarrq. Oxaliplatin+5-FU /LV in adjuvant colon cancer Result of the international randomized MOSAIC trial[J].Pree AM Soc Clin Onco,2003,(03):1015a.
9Goldberg RM,Sargent DJ,Morton RF. A randomized controlled trial of fluorouracil plus leucovofin,irinoteean,and oxalipatin combinations in patients with previously untreated metastatic colorectal cancer[J].Journal of Clinical Oncology,2004,(01):23-30.doi:10.1200/JCO.2004.09.046.
10Recchia F,Nuzzo A,Lalli A. Multicenter phase Ⅱ study of CTP-11 fractionated over two days with bimonthly leucovorin and 5-fluorouraeil in patients with metastatic cdorectal cancer[J].Anticancer Research,2003,(3C):2903-2908.
