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异丙酚的镇痛作用及其机制 被引量:20

Propofol Analgesia and its mechanism
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摘要 睡眠剂量和亚睡眠剂量的异丙酚具有镇痛作用。其镇痛作用主要与增强GABA_A受体功能、拮抗NMDA受体、增强阿片受体活性和抑制一化氮合成酶(NOS)活性等密切关联。深入研究异丙酚镇痛作用及其机制,对临床更合理地应用异丙酚具有重要的意义。
出处 《国外医学(麻醉学与复苏分册)》 2005年第6期358-361,共4页 Foreign Medical Sciences(Anesthesilolgy and Resuscitation)
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