细胞凋亡与急性呼吸窘迫综合征
Apoptosis and Acute Respiratory Distress Syndrome
摘要
细胞凋亡在急性呼吸窘迫综合征(ARDS)的发病机制中起重要作用,其中两类细胞凋亡在肺部炎症反应及肺损伤中扮演了重要角色,其一是多形核中性粒细胞的凋亡延迟,从而导致中性粒细胞介导的炎症反应增强；其二是肺泡上皮细胞的凋亡性死亡,与ARDS也密切相关。现就近年来ARDS发病机制中细胞凋亡的研究进展作一综述。
出处
《国外医学（麻醉学与复苏分册）》
2005年第6期375-377,共3页
Foreign Medical Sciences(Anesthesilolgy and Resuscitation)
参考文献18
-
1Abraham E.Neutrophils and acute lung injury.Crit Care Med.2003,31(4Suppl):195 - 199.
-
2Hashimoto S,Kobayashi A,Kooguchi K,et al.Upregulation of two death pathways of perforin/granzyme and FasL/Fas in septic acute respiratory distress syndrome.Am J Respir Crit Care Med,2000,161:237 -243.
-
3Matute- Bello G,Liles WC,Radella Ⅱ F,et al.Modulation of neutrophil apoptosis by G - CSF and GM - CSF during the course of ARDS.Crit Care Med,2000,28:1 -7.
-
4Aggarwal A,Baker CS,Evans TW,Haslam PL.G -CSF and IL -8 but not GM - CSF correlate with severity of pulmonary neutrophilia in acute respiratory distress syndrome.Eur Respir J,2000,15:895 -901.
-
5Lesur O,Kokis A,Hermans C,et al.Interleukin-2 involvement in early acute respiratory distress syndrome:relationship with polymorphonuclear neutrophil apoptosis and patient survival.Crit Care Med,2000,28:3814-3822.
-
6Power CP,Wang JH,Manning B,et al.Bacterial lipoprotein delays apoptosis in human neutrophils through inhibition of caspase -3 activity:regulatory roles for CD14 and TLR-2.J Immunol.2004,173:5229 -5237.
-
7Parsey MV,Kaneko D,Shenkar R,et al.Neutrophil apoptosis in the lung after hemorrhage or endotoxemia:apoptosis and migration are independent of IL- 1beta.Clin Immunol,1999,91:219 -225.
-
8Sookhai S,Wang JJ,McCourt M,et al.A novel therapeutic strategy for attenuating neutrophil - mediated lung injury in vivo.Ann Surg,2002,235:285 -291.
-
9Hirano T,Hirasawa H,Oda S,et al.Modulation of polymorphonuclear leukocyte apoptosis in the critically ill by removal of cytokines with continuous hemodiafiltration.Blood Purif,2004,22:188-197.
-
10Kirkham PA,Spooner G,Rahman I,et al.Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products.Biochem Biophys Res Commun,2004 ,318:32-37.
-
1Konturek PC,李晓波,刘文忠.CagA^+幽门螺杆菌通过诱导细胞凋亡延迟小鼠胃溃疡愈合[J].胃肠病学,1999,4(1):28-28.
-
2张银中.多形核中性粒细胞、内皮细胞与ARDS[J].国外医学（麻醉学与复苏分册）,1998,19(6):359-362. 被引量：1
-
3大动脉炎诊断及治疗指南[J].中华风湿病学杂志,2011,15(2):119-120. 被引量：105
-
4董辉,张文远.中性粒细胞弹性蛋白酶在炎症性肠病中的研究进展[J].实用医院临床杂志,2014,11(1):193-196. 被引量：8
-
5杜丽娟,唐学贵,李敏.细胞凋亡与溃疡性结肠炎关系的研究进展[J].医学综述,2010,16(24):3702-3704. 被引量：3
-
6焦光宇,聂志伟,刘春利,李承峰,刘冬娟,何平.小剂量脂多糖气管内滴注制备急性肺损伤动物模型的探究[J].中国实验动物学报,2007,15(4):292-295. 被引量：28
-
7彭高农.羟基脲可纠正镰状细胞贫血患者多形核中性粒细胞的L-选择素表达异常及H_2O_2产物增多[J].国外医学（内科学分册）,2003,30(9):412-412.
-
8马彪,凌宏.急性高胆固醇血症多形核中性粒细胞在家兔急性心肌梗塞再灌注中的损伤作用[J].湖北医学院学报,1992,13(2):97-102.
-
9李建新,丁甫月,伍欣星.过敏性紫癜患儿治疗前后淋巴细胞凋亡情况分析[J].临床儿科杂志,2005,23(8):547-548.
-
10郑冬图,斯银平,王艳红.1例患大动脉炎疗养员的护理[J].医学信息,2013(8):481-481.
