高原正常人群TCD异常频谱形态特点研究

Research in the Characteristics of TCD Abormal Spectrum Contour of Normal Person Group at High Altitude

目的:研究高原地区正常人群TCD(经颅多普勒)异常频谱形态的特点。方法:应用TCD技术检测和分析高原不同年龄段正常人群脑动脉的频谱形态(n=432)。使用SPSS11.5统计软件进行χ2检验和Pearson相关分析。结果:峰时后延型异常频谱的发生率在前循环为27.31%,在后循环为43.51%,其差异在40～69岁间具有显著性(χ2=6.9438～14.6794,P=0.0001～0.0085),女性高于男性(χ2=7.3476～28.7575,P=0.0000～0.0067)。60岁以上人群出现高阻力型异常频谱,发生率为14.93%,男性高于女性(χ2=13.0663,P=0.0003)。异常频谱出现率与年龄(γs=0.6352～0.6786,P=0.0000)和搏动指数(γs=0.3126～0.3630,P=0.0000)呈正相关。结论:高原地区正常人群中,峰时后延型异常频谱主要见于女性和后循环,高阻力型异常频谱主要见于老年男性。

Oblectlve： To research the characteristics of TCD （Transcranlal Doppler） abnormal spectrum contour of normal person group on plateau. Methods： Detecting and anglicizing the TCD spectrum contour of cerebral arterial blood of normal person group on plateau by TCD （n = 432）. Statistical processing： Using the Chl-sauare test and Pearson correlation analysis of SPSS11.5 software. Results： The Incidence of abnormal spectrum-peak-back-shift iS 27.31% In the anterior circulation and It is 43.51% in the Posterior circulation with Statistical difference In 40- 69years old group （ ^=6.9438-14.6784, P= 0.0001 - 0.0085） and higher In female than In male. （ χ^ = 7.3476- 28.7575, P=0.0000-0.0067）. The incidence of abnormal spectrum-high-resistance Is 14.93% beyond 60 years old group and higher In male then In female （χ^2=13.0663, P=0.0003）. The Incidence of anomaly spectrum is positive related to age （ γs=0.6352-0.6786,P=O.0000）and PI（γs=0.3126-0.3630,P=0.0000）. Conclusion. In normal person group at high altltucle, the abnormal spectrum-peak-back-siift Is more common In female and the posterior circulation. The abnormal spectrumhigh-resistance is more common In old male.