影响乳腺癌术后患者生存质量的因素分析及中药干预的作用

Analysis of Factors on Quality of Life in Patients with Breast Cancer After Surgery and Therapeutic Effect of Chinese Herbal Medicine

【目的】探讨影响乳腺癌术后患者生存质量(QOL)的因素以及中药干预的作用。【方法】采用简单随机法将120例乳腺癌术后患者随机分为治疗组(61例)和对照组(59例),治疗组服用癌复康胶囊(主要由黄芪、茯苓、白术、太子参、淮山药、肉苁蓉、山茱萸、女贞子、制首乌、莪术、半枝莲、薏苡仁等组成),对照组未服用癌复康胶囊。引入乳腺癌生存质量专用量表EuroQLQ-BR23进行QOL调查,采用累加Logit回归模型分析调查结果。【结果】对乳腺癌术后患者生存质量总分等级有影响的因素为组别、流产次数、腋下淋巴结转移情况、生育儿女数和病理类型,其中OR值的点值估计大于1的有组别、流产次数和腋下淋巴结转移,OR值的点值估计小于1的有生育儿女数和病理类型。【结论】影响乳腺癌术后患者生存质量的因素有流产次数、生育儿女数、腋下淋巴结转移情况、病理类型和中药干预,其中中药癌复康治疗是一个重要的保护因素。

[ Objective] To investigate the effect of herbal preparation of Aifukang on quality with breast cancer after surgery. [ Methods] One hundred and twenty patients with breast of life （QOL） in patients cancer after surgery were allocated to group A （ n = 61 ） and group B （ n = 59） according to random number table. Aifukang was given to Group A but not to group B. The QOL was determined with EuroQLQ-BR23 questionnaire and was analyzed by cumulative Logits regression. [ Results ] The influencing fhctors on the classification of QOL score were grouping, abortion times, metastasis in axillary lymph nodes, the number of bearing child and pathological type. Among the above factors, OR 〉 1 was found in grouping, abortion times and metastasis in axillary lymph nodes, and OR 〈 1 in the number of bearing child and pathological type. [Conclusion] The QOL influencing factors are nodes metastasis and pathological type, and Aifukang treatment is beneficial breast cancer after surgery. grouping, abortion times, axillary lymph to the improvement of QOL in patients with