养血祛风法对表皮移植术治疗白癜风疗效的影响

Effect of Blood-nourishing and Wind-expelling Therapy Combined with Epidermic Grafting for Vitiligo

【目的】观察养血祛风法对表皮移植术治疗白癜风疗效的影响。【方法】采用简单随机法将62例白癜风患者随机分为两组。对照组30例,采用白癜风治疗仪进行发疱及磨削术将正常皮肤表皮移植到白斑区;治疗组32例,在采用对照组的表皮移植术基础上,于术后2周开始服用自拟中药白驳风汤(当归、鸡血藤、防风、补骨脂、赤芍、丹参、白芷、黄芪、红花)治疗,隔日1剂,同时外擦中药复补酊(补骨脂、白芷、丹参、红花),2次／d。观察两组的近期疗效和远期随访结果。【结果】治疗组的痊愈率为83．6％、有效率为93．1％,对照组的痊愈率为71．0％,有效率为88．5％,治疗组疗效优于对照组(P<0．05);远期随访结果显示,治疗组已成活皮片的色素再脱失率低于对照组(P<0．05)。【结论】养血祛风为主中药能提高表皮移植术治疗白癜风的近期治愈率和降低远期色素再脱失率。

[ Objective] To observe the influence of blood-nourishing and wind-expelling therapy on the therapeutic effect of epidermic grafting for vitiligo. [ Methods ] Sixty-two patients with vitiligo were allocated to group A （n = 32） and group B （ n = 30） with simple random method. Group B was treated with epidermic grafting. Group A was treated with Saposhnikoviae, Fructus Psoraleae, Radix Paeoniae Rubra , Radix Salviae Miltiorrhizae, etc.） 2 weeks after epidermic grafting was performed, one dose every other day, and with external application of Fubu tincture （composed of Fructus Psoraleae, Radix Angelicae Dahuricae, Radix Salviae Miltiorrhizae and Flos Carthami） bid. After treatment, the short-term and long-term therapeutic effect was observed in the two groups. [Results] The cure rate was 83.6% and the effective rate was 93.1% in group A, and respectively 71.0% and 88.5% in group B, the therapeutic effect of group A being better than that of group B （ P 〈 0.05）. For the long-term effect, the depigmentation rate was lower in group A than that in group B （P 〈 0.05）. [ Conclusion] Herbs with the actions of nourishing blood and expelling wind can enhance the short-term effect of epidermic grafting for vitiligo and decrease the depigmentation rate.