C肽、血脂水平与2型糖尿病下肢血管病变的关系

The relation of C-peptide,blood lipoid and pathologic change of pelvic limb blood vessels in type 2 diabetes

目的探讨2型糖尿病患者下肢血管病变的危险因素。方法应用美国GE公司LOG-IQ700型超声诊断仪,对2型糖尿病患者131例下肢动脉进行检测,将下肢血管病变组74例与非下肢血管病变组54例进行对照,记录患者年龄、病程、空腹及餐后血糖、糖化血红蛋白、血脂、空腹及餐后C肽。结果糖尿病下肢血管病变组患者年龄大、病程长、LDL-C明显升高、空腹及餐后C肽明显降低。结论年龄、病程、高血糖、高血脂、低C肽水平是糖尿病下肢血管病变的危险因素,糖尿病神经病变与大血管病变正相关。

Objective ：To investigate the relevant risk factors of pathdogic changes of pelvic limb blood vessel diseasa in type 2 diabetes. Methods： There were 131 NIDDM patients were checked arterials in pelvic limbs by ultrasonography. There were 74 prtients in pathologic change group and 54 patients in non-pathologic change group. Record ages,disease dlstance, empty and full abdomend blood glucose and C-peptide ,glychohemoglobin , blood lipoid . Results ：patients in pathologic change group were older and had longer stadium ,whose LDL-C increased much higher , C-peptide of empty and full abdomend decreased more significantly then patients of non-pathologic change group. Conclusion：Age, stadium , high blood glucose and lipid ,and low C-peptide leveal are factors of pathologic change of pelvic limb blood vessels in diabetes ,and neural pathologic changes are positive with great vessels pathologic changes are positive with great vessels pathologic changes.