摘要
采用均匀设计，以乳剂的稳定性参数为考察指标，考察了初乳乳化剂、复乳乳化剂、乳化时间等因素对复乳稳定性的影响；筛选出Ｗ／Ｏ／Ｗ型甘草酸单铵盐口服复乳的优化处方和工艺，并对复乳的主要理化特性和物理稳定性进行了考察。
Multiple emulsion(W/O/W) containing ammonium glycyrrhizinate was formulated by uniform design investigating the factore suchas emulsifiers of primary emulsion and multiple emulsion, period of emulsification etc. Its particle size, flow type, microphotographic structure, yield of multiple emulsion and Physical stability were determined. Results showed that the multiple emulsion had good stability.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1996年第1期8-11,共4页
Chinese Journal of Pharmaceuticals
关键词
甘草酸单铵盐
复乳
ammonium glycyrrhizinate, multipe emulsion, uniform design, properties
