CT引导下经皮肺活检对肺内占位病变的诊断价值

The Diagnostic Value of CT-guided Percutaneous Lung Biopsy of Lung Lesions

目的:探讨CT引导下经皮肺活检法对肺内占位病变的诊断价值和安全性。方法:采用CT引导下经皮肺活检法对 119例肺内占位病变进行穿刺活检,分析其敏感性、确诊率、并发症及相关因素。结果:穿刺病理确诊为恶性肿瘤79例,经手术及临床观察确诊恶性肿瘤5例,良性痛变共35例。灵敏度为94．0％(79／84),特异度100％(35／35),假阴性4．2％(5／ 119),无假阳性,总确诊率为95．8％(114／119)。术后气胸发生率16．0％(19／119),咯血发生率20．2％(24／119),血胸及脑梗死发生率均为1．7％(2／119)。结论:CT引导下经皮肺活检法相对安全、易行,确诊率高,对肺内占位病变确诊具有重要意义。

Objective： To evaluate the diagnostic value and the safety of CT-guided pereutaneous lung biopsy of lung nodules. Methods：Datas of 119 cases lung nodules who underwent CT guided percutaneous lung biopsy were studied. The sensitivity with diagnositic accuracy and complications were analyzed. Results.. There were total 84 case of malignant tumor and 35 cases of benign lesion. 79 cases of malignant tumor and 35 cases with benign lesion were diagnosed by CT-guided purcutaneous lung biopsy. 5 cases were diagnosed through clinical observation or operation. The diagnositic sensitivity and accuracy were 94. 0%（79/84） and 100%（35/35） respectively. False negative rate and false positive rate were 4, 2% and 0% respectively. The overall accurate rate was 95. 8% （114/119）. Incidence of post-biopsy pneumothorax, hyrnoptysis, thoracic cavity bleeding and cerebral infarction were 16.0%（19/119）, 20. 2%（24/119）, 1.75（2/119） and 1.75（2/119） respectively. Conclusion： CT-guided percutaneous lung biopsy is relatively safe and has high diagnositic accuracy in lung lesions.