蚯蚓抗菌的免疫生态学研究进展

Research advance in antibacterial immunity ecology of earthworm.

蚯蚓生活于病原菌丛生的环境中,却极少患病,这与蚯蚓自身独特的抗菌与免疫系统相关.本文从蚯蚓的防御屏障、细胞免疫和体液免疫3个方面对蚯蚓的抗菌免疫系统进行了综述.其中,蚯蚓的防御屏障主要包括体壁、体表粘液和消化道;细胞免疫主要包括吞噬作用和包囊作用;体液免疫则是以非特异性免疫为主.蚯蚓体液中具有抗菌作用的物质主要包括凝集素、抗菌蛋白、抗原结合蛋白以及溶菌酶等.

Earthworm lives in the environment flocked with pathogens, but few are infected due to the earthworm＇s unique antibiotic and immune system. In this paper, the research advance in this domain was reviewed from the aspects of antibiotic barrier, cell immunity, and humoral immunity. Antibiotic barrier mainly includes body wall, alimenta- ry canal and parietal mucus, cell immunity represents phagocytosis and encapsulation responses, while humoral immunity gives priority to unspecific immune system. The main antibacterial materials in the coelomic fluid of earthworm are antigenobinding proteins, agglutinins, antibacterial proteins, and lysozyrne.