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Livin及其在肿瘤表达的研究进展 被引量:1

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摘要 Livin是近年发现的一个凋亡蛋白抑制因子,主要通过抑制胱天蛋白酶-3、-7、-9(caspase -3、-7、-9)的活性来阻断细胞凋亡过程。Livin在多种肿瘤细胞中表达,其抑制细胞凋亡,与肿瘤的发生、发展及预后相关,有望成为肿瘤治疗的新靶点。
作者 唐乔 黄金中
出处 《中国医学文摘(耳鼻咽喉科学)》 2006年第1期37-39,共3页 Chinese Medical Digest(Otorhinolaryngology)
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  • 1Yagihashi A,Asanuma K,Kobayashi D,et al.Detection of autoantibodies to Livin and Survivin in sera from lung cancer patients.Lung Cancer,2005,48(2):217-221.
  • 2Vucic D,Stennicke HR,Pisabarro MT,et al.ML-IAP,anovel inhibitor of apoptosis that is preferentially expressed in human melanomas.Curr Riol,2000,10(21):1359-1366.
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  • 4李百鸥,王永来.凋亡抑制蛋白Livin在卵巢癌中的表达[J].山东医药,2008,48(14):51-52. 被引量:3
  • 5梁春艳,马萍.凋亡抑制蛋白Livin:抗癌新靶点[J].现代肿瘤医学,2008,16(6):1055-1058. 被引量:10
  • 6黄伟.Caspase研究进展[J].国外医学(输血及血液学分册),2001,24(4):292-294. 被引量:15

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