钙化上皮瘤及牙源性钙化上皮瘤的临床病理分析

The clinicopathological analysis of calcifying epithelioma and calcifying epithelial odontogenic tumor

目的:探讨钙化上皮瘤及牙源性钙化上皮瘤的临床表现、诊断及外科处理原则。方法:对13例钙化上皮瘤和4例牙源性钙化上皮瘤患者的临床资料进行回顾性分析。结果:所有患者均经手术治疗。钙化上皮瘤患者平均年龄11.2岁,小于10岁者占69.2%(10例);位于头颈部8例(61.5%),四肢4例(30.8%),躯干1例(7.7%)。牙源性钙化上皮瘤患者平均年龄38.75岁,均位于颌骨。两种肿瘤无明显性别差异,均有复发、恶变的报道。结论:钙化上皮瘤和牙源性钙化上皮瘤在临床表现和病理诊断上具有明显差别,是两种不同的肿瘤;牙源性钙化上皮瘤具有局部浸润性生长,手术切除必须彻底。

Objective： To discuss the clinical presentations , diagnosis and management guidelines of calcifying epithelioma （CE） and calcifying epithelial odontogenic tumor （CEOT）. Method： 13 cases of CE and 4 cases of CEOT were retrospected. Result： All patients were treated surgically. The average age of CE patients was 11.2 years old . 69.2% （ 10 cases） was less than 10 years old. The lesions located on the head and neck in 8 cases （61.5%）, on the arms and legs in 4 cases （30.8%） and on the trunk in 1 case （7.7%）. The average age of CEOT patients was 38.75 years old. All CEOT lesions located on the mandible or maxilla. There was no obvious sexual difference in both tumors. Both were reported for recurrent and malignant cases. Conclusion： CE and CEOT are obviously different in clinical presentations and pathological diagnosis. Complete surgical excision was necessary for CEOT.