摘要
用Ｇｅｎｅｐｒｏ程序在计算机上对抗肌萎缩蛋白基因缺失热区部分４４号、５０号和５１号内含子进行分析，结果表明该基因缺失热区ＡＴ（腺嘌呤－胸腺嘧啶）含量高，呈聚集性分布。并存在多个同源顺序。该结果支持作者以前提出的“不同内含子中ＡＴ富集区的同源顺序与ＤＮＡ缺失有关”的结论。
he partial intron 44 , 50 ,and 51 of deletion hot spot in the dystrophin gene was analyzed by software :Genepro. The results showed that the deletion hot spots contained an aggregated AT-rich sequences in different introns. The results support the idea , which the autbors sug- gested before , that the homologues sequences among the AT-rich regions are related to the DNA deletion.
出处
《中山医科大学学报》
CSCD
1996年第1期5-8,共4页
Academic Journal of Sun Yat-sen University of Medical Sciences
关键词
肌萎缩
遗传学
基因缺失
序列同源性
muscular atrophy/genetics
gene deletion
sequence homology
