BiPAP呼吸机治疗COPD合并II型呼吸衰竭62例临床研究

Clinical Study of BiPAP Ventilation Therapy for 62 Cases of COPD Patients with Type II Respiratory Failure

目的：探讨（鼻）面罩双水平气道正压通气（BiPAP）治疗在慢性阻塞性肺部疾病（COPD）合并Ⅱ型呼吸衰竭有无肯定疗效。方法：62例COPD合并呼吸衰竭患者应用BiPAP呼吸机辅助通气治疗，记录通气治疗前及通气治疗2-4h、2，4h后患者的血气分析、心率、呼吸频率。结果：治疗前、治疗后2，4h、治疗后24h氧分压、二氧化碳分压、心率、呼吸频率比较有显著差异（P〈0．05）。结论：应用BiPAP呼吸机辅助通气治疗COPD合并Ⅱ型呼吸衰竭临床上有肯定疗效。

Objective： To study the effects of bilevel positive airway pressure（BiPAP） on type Ⅱ respiratory failure in chronic obstructive pulmonary disease（COPD） patients. Methods： Sixty-two COPD patients with type Ⅱ respiratory failure were treated by BiPAP. The datum of the blood gas levels, heart rate and respiratory rate were made before and after the ventilation. Results： Before and after the therapy, the differences of arterial carbon dioxide tension, arterial oxygentension, heart rate and respiratory rate were significant （ P 〈 0.05）. Conclusion： BiPAP respiratory machine assistant ventilation is effective and worthy of being widely used in the treatment of COPD patients who have type Ⅱ respiratory failure.