高血压致颈动脉损伤的临床意义

The Characteristics of Carotid Plaque in Patients with Ischemic Cerebrovascular Disease and Hypertension

目的探讨高血压致颈动脉损害的特点及与脑梗死的关系,为脑卒中的预防提供临床指标。方法对71例高血压合并脑梗死病人、30例高血压病人及38例健康对照者进行颈动脉彩色血管超声检测。结果①高血压及高血压合并脑梗死病人颈动脉斑块发生率与正常对照组比较均有统计学意义。②不稳定斑块的发生率在高血压伴脑梗死组明显高于其他两组。结论①高血压致颈动脉损害可导致斑块形成;②不稳定斑块是脑卒中的预测因子。

Objective The purpose of this study was to investigate the Characteristics of atherosclerosis severity degree in extracranial carotid arteries in patients （pts） with ischemic cerebrovascular disease and to provide clinical index for thc prophylaxis of：ischemic cerebrovascular disease. Methods Seventy- one pts with ischemic cerebrovascular disease and hypertension, 30 pts with hypertension and 38 healthy controls were detected by color-Doppler ultrasound. Results ① The prevalence of plaque of extracranial carotid arteries in pts with ischemic cerebrovascular disease and hypertension and pts with hypertension was different significantly compared with that in healthy controls. ②The prevalence of unstable plaque of extracranial carotid arteries in pts with ischemic cerebrovascular disease was more than that in other two groups. Conclusion ①Hypertension might caused the prevalence of plaque in extracranial carotid arteries. ②The unstable plaque in extracranial carotid arteries was a predicting factor for ischemic cerebrovascular disease.